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OCR: As ordinar performed (Fig. 20.18) plas hor very C-peptide assay is neither very sensitive specially inspecific; false-positive results can occur, ue to patients with factitious hypoglycaemia d onses can sulphonylurea abuse. False-negative res ptide also occur because of suppression of C-p ossibly duesecretion in patients with insulinomas, line levels. to increases in circulating plasma adrena insulin Both the sensitivity and specificity of the singan hypoglycaemic test can be improved by u in under infusion of low doses of exogenous insu n a controlled conditions in order to mainta constant and reduced blood sugar level ( s is hypoglycaemia clamp procedure), but th over expensive, tedious and has no advantage ernight or simpler tests such as measurement of or levels, fasting insulin, C-pep ...